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Forestry, Wildlife, and Fisheries

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C.A. Speer

Emeritus Professor

Email: caspeer@utk.edu

 

C.A. Speer is a former B. Ray Thompson Distinguished Professor of Cellular and Molecular Immunology in the Department of Forestry, Wildlife and Fisheries, and founding Director of the University of Tennessee's Center for Wildlife Health.

Professional Preparation:
Colorado State University                    Zoology & Entomology B.S.                             1967
Utah State University                            Microbiology & Parasitology M.S.                    1969
Utah State University                            Microbiology & Parasitology Ph.D                   1972
University of New Mexico                     Malaria Immunology  - Postdoc                  1973-75

Professional Appointments:
2002-2007:  B. Ray Thompson Distinguished Professor of Cellular and Molecular Immunology; Director, Center for Wildlife Health, Department of Forestry, Wildlife and Fisheries, University of Tennessee, Knoxville.
2000-2002:  Dean and Professor, College of Agricultural Sciences and Natural Resources and the Tennessee Agricultural Experiment Station, Institute of Agriculture, University of Tennessee, Knoxville.
1999-2000:  Director, Center for Bison and Wildlife Health, Montana State University, Bozeman.
1994-2000:  Professor of Veterinary Molecular Biology, Montana State University, Bozeman;  
1986-1994:  Head and Professor, Veterinary Molecular Biology, Montana State University, Bozeman; 
1983-1986:  Associate Professor of Veterinary Science and Director of Agricultural Experiment Station Electron Microscope Facility, Montana State University, Bozeman;  
1975-1983:  Assistant Professor and Associate Professor and Director of Electron Microscope Facility, Department of Microbiology, University of Montana, Missoula;  
1973-1975:  Research Associate (Postdoctoral Fellow), Malaria Immunity and Vaccination Program, Department of Biology, University of New Mexico, Albuquerque;
1972-1973:  Assistant Professor, Department of Histology, University of Texas Medical Center, Houston.

Selected Publications: (C.A. Speer has published more than 190 articles in peer-refereed journals)
Speer, C.A., D.W. Reduker, D.E. Burgess, W.M. Whitmire and G.A. Splitter.  1985.  Lymphokine-induced inhibition of growth of Eimeria bovis and Eimeria papillata (Apicomplexa) in cultured bovine monocytes.  Infect. Immun. 50:566-571.
Speer, C.A., W.E. Severson, H.J. Cranston, D. Scollard, J.R. Thompson and M.W. White.  1992.  A diagnostic DNA assay for trichomoniasis in cattle.  Proceedings  Livestock Conservation Institute, pp. 128-137.
Speer, C.A., M. Tilley, M.E. Temple, J.A. Blixt, J.P. Dubey and M.W. White.  1995.   Sporozoites of Toxoplasma gondii lack dense-granule protein GRA3 and form a  unique parasitophorous vacuole.  Mol. Biochem. Parasitol. 75:75-86.
Eda, S., B. Elliott, M.C. Scott, W.R. Waters, J. Bannantine and C.A. Speer.  2004.  New method of serological testing for Mycobacterium avium subsp. paratuberculosis  (Johne’s disease) by flow cytometry.  Foodborne Pathogens and Disease 2:250-262.
Speer, C.A., M.C. Scott, J.P. Bannantine, W.R. Waters, Y. Mori, R.H. Whitlock and S. Eda.  2006.  A novel enzyme-linked immunosorbent assay for the diagnosis of Mycobacterium avium subsp. paratuberculosis infections (Johne’s disease) in cattle.  Clinical and Vaccine Immunology 13: 535-540.
Eda, S., J.P. Bannantine, W.R. Waters, Y. Mori, R.H. Whitlock, M.C. Scott and C.A. Speer.  2006.  A highly sensitive and subspecies-specific surface antigen enzyme-linked immunosorbent assay for the diagnosis of Johne’s disease.  Clinical and Vaccine Immunology 13: in press.
Speer, C.A., R.B. Wong and R.H. Schenkel.  1983.  Effects of monoclonal IgG antibodies on Eimeria tenella (Coccidia) sporozoites.  J. Parasitol. 69:775-777.
Speer, C.A., R.B. Wong, J.A. Blixt and R.H. Schenkel.  1985.  Capping of immune complexes by sporozoites of Eimeria tenella.  J. Parasitol. 71:33-42.
Reduker, D.W. and C.A. Speer.  1986.  Proteins and antigens of merozoites and sporozoites of Eimeria bovis (Apicomplexa).  J. Parasitol. 72:901-907.
Speer, C.A. and W. M. Whitmire.  1989.  Shedding of the immunodominant P20 surface antigen of Eimeria bovis.  Infect. Immun. 57:999-1001.
Leid, J.G., D. Hunter and C.A. Speer.  2002.  Early diagnosis of Johne’s disease in the American bison by monoclonal antibodies directed against antigen 85.  Ann. NY Acad. Sci. 969:66-72.

Synergistic activities:
Founding Director, Center for Wildlife Health, Department of Forestry, Wildlife and Fisheries, Tennessee Agricultural Experiment Station, Institute of Agriculture, University of Tennessee.
Committee member, curriculum development for the Wildlife Health Concentration for bachelor of science degree, College of Agricultural Sciences and Natural Resources, University of Tennessee.
Co-discoverer with S. Eda of the UT diagnostic test for Johne’s disease in beef and dairy cattle.
U.S. Patent Application Serial No. 10/832,761, Filed:  April 27, 2004.  Method for diagnosing infectious diseases.  Inventors:  S. Eda and C.A. Speer.
U.S. Patent Application Serial No. 11/220,156, Filed September 6, 2005.  Method for diagnosing infections.  Inventors:  C.A. Speer and S. Eda.

Collaborators:
J.P. Dubey (ARS, USDA, Beltsville); S. Eda (University of Tennessee);  R. Cawthorn and S. McKenna (College of Veterinary Medicine, University of Prince Edward Island, Canada);  Y. Mori (National Institute of Animal Health, Tsukuba, Japan); Jenks Britt (Western Kentucky University);  R. Wilson (State Veterinarian, State of Tennessee);  R. Whitlock (Veterinary Medicine, University of Pennsylvania);  C. Easterly (Oak Ridge National Laboratory);  J. Bannantine and Ray Waters (National Animal Disease Center, USDA, Ames);  C. Hudson (U.S. Fish and Wildlife Service, Bozeman, Montana);  C. Moffatt, Moffatt Veterinary Clinic, Athens, Tennessee);  D. Hunter (Turner Enterprises, Bozeman, Montana);  W. Marquardt (Colorado State University, Fort Colllins);  J. Leid (Northern Arizona University);  D. Lindsay (College of Veterinary Medicine, Virginia Tech);  J. A. Blixt (Montana Veterinary Diagnostic Laboratory, Bozeman);  M. Anderson (UT Medical Hospital, Knoxville).

Graduate students and Postdoctoral Fellows: 
Past graduate students:  T.G. Douglass, J.J. Ferraroni, S.G. Reed, A.M. Shatry, and W.M. Whitmire.  M.S. students:  S.E. Clark, C. Hudson, J.E. Kyle, K. Liaw, E. MacConnell, G. Mukherjee, P.V. Nash, A.T. Olcott, G.J. Sibert, and W.M. Whitmire,  Taylor Fielden.
Past Postdoctoral Fellows:  D.W. Reduker, N.P. Robertson, H.P.A. Hughes, M. Tilley, and J.G. Leid.